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KMID : 0361120050190020215
Korean Journal of Transplantation
2005 Volume.19 No. 2 p.215 ~ p.218
A Case of Cytomegalovirus (CMV) Panniculitis after Renal Transplantation
¹èÈ£»ó/Bae HS
ÀÌÇöö/Çö½ÂÇý/ÃÖÁö¿µ/¹ÚÀÚ¿ë/¹Ú¼º¿ø/±èÂù´ö/¹Ú¼±Èñ/±è¿ë¸²/Lee HC/Hyun SH/Choi JY/Park JY/Park SW/Kim CD/Park SH/Kim YL
Abstract
Cytomegalovirus (CMV) remains an important pathogen in organ transplant patients. However, cutaneous lesions are rare manifestation of systemic CMV infection. We report a case of CMV panniculitis in a 47-year-old renal transplant recipient. She admitted due to fever, local pain in the left pelvic area, and erythematous tender palpable mass for 2 weeks. Twenty years ago, she underwent renal transplantation and had taken azathioprin 100 mg and prednisone 10 mg daily. Serum creatinine had been preserved between 2.5 and 3.5 mg/dL. Bacterial, fungal, and AFB cultures of skin lesion and drained pus were negative. CMV antigenemia was noted. Skin biopsy revealed multinucleated dermal histiocytes and positive for CMV antibody by immunohistochemical staining. Polymerase chain reaction testing of skin tissue and drained pus revealed CMV DNA. She was treated with ganciclovir for four weeks and skin lesion was completely resolved without recurrence.
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